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2015年10月26日 星期一

New IHC Antibodies

Abnova offers 200+ new antibodies with high specificity and sensitivity for a great variety of applications including enzyme-linked immunosorbent assay (ELISA), immunocytochemistry (ICC), immunofluorescence (IF), immunohistochemistry (IHC) and flow cytometry. Among the new antibodies, we gladly introduce 193 antibodies for immunohistochemistry (IHC) staining with high consistancy to accelerate your research. Please check the following information of new antibodies:

New IHC Antibodies:
Angiogenesis Apoptosis Binding
(Nucleic Acid/Others)
Cell Ad/Junc/Cytoskel
Cell Cycle Cytokine Enzyme
(Kinase/Others)
Membrane
(Transporter/Receptor/Others)
Metabolism Neurobiology Plasma/Serum Signal Transduction
Stem Cell Transcriptions Ubiquitin Others

Featured IHC Antibodies:
Catalog # Product Name
PAB29557 MAP1LC3A (Cleaved) polyclonal antibody
PAB29558 MAP1LC3A polyclonal antibody
MAB12245 FTL monoclonal antibody, clone 6E10E4
MAB12260 CD68 monoclonal antibody, clone 3F7D3
MAB12264 CDKN2A monoclonal antibody, clone 1D7D2A1

Other New Antibodies:

Apoptosis Binding
(Nucleic Acid/Others)
Cell Ad/Junc/Cytoskel Cell Cycle
Enzyme
(Kinase/Others)
Membrane
(Transporter/Receptor/Others)
Metabolism Ubiquitin

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2015年8月5日 星期三

Cytoskeleton

New Discoveries on Cytoskeletons
  • Self-organization of actin cytoskeleton, the dynamic of radial fibers-transverse fibers system, takes crucial role in developing the left-right asymmetry in tissues and embryos. (Nature Cell Biology,2015)
  • Apical and basolateral spectrin cytoskeletons, potential mechano-sensors, regulate Hippo signaling pathway in response to human epithelial cell density. (EMBO,2015)
  • Cytoskeleton-associated proteins, CRMP2/DPYSL2, TPM2, TCP1ε and 14.3.3γ, can be potential biomarkers for small-intestinal neuroendocrine tumors invasion. (Molecular and Cellular Endocrinology,2015)

Cytoskeleton Compositions
(Click to see your products of interest)

Proteins Involved in Cytoskeletons
(Click to see your products of interest)
Actin Polymerization
Protein Function/Activity
Cofilin Dissociation from (-) end
Severin Severing, capping (+) end, control of length of actin filaments; essential for branch formation
Gelsolin Severing, capping (+) end, control of length of actin filaments; essential for branch formation
CapZ capping protein Capping (+) end, stabilize F-actin prevent disassembly during muscle contraction
Tropomodulin Capping (+) end, stabilize F-actin prevent disassembly during muscle contraction
ARPC 2/3 Capping (-) end, side binding and nucleation
Classes of Intermediate Filaments
Protein Function/Activity
I. Acidic cytokeratins Mechanical strength
II. Basic cytokeratins Mechanical strength
III. Vimentin
III. Desmin
III. GFAP
Maintenance of cell shape
Structural support for contractile machinery
Maintenance of cell shape
IV. Neurofilament
(NEFL,NEFM,NEFH)
Axon strength; Determines axon size
V. Nuclear Lamins
(Lamin A, Lamin B)
Form nuclear scaffold and shape the nucleus
VI. Nestin Unknown
Modulation of Microtubule Dynamics
Protein Function
MAP1 Assembles and stabilizes microtubules
MAP2 Assembles and cross-links microtubules to one another and intermediate filaments
MAP4 Stabilizes microtubules
MAPT Assembles and stabilizes and cross-links microtubules
RSN/CLIP1 Cross-links microtubules to chromosomes and endosomes
Katanin Microtubule severing
STMN1/OP18 Binds to tubulin dimers

Eight Product Categories and 2100+ Products

Featured Products
TUBA1A monoclonal antibody (M06), clone 2D2
H00007846-M06
Immunofluorescent staining of HeLa cell using TUBA1A monoclonal antibody (Cat #H00007846-M06) at 10ug/ml.

ACTA monoclonal antibody (M02), 4A8-2H3
H00000059-M02
Detection limit for recombinant GST tagged ACTA2 using ACTA2 monoclonal antibody (Cat # H00000059-M02) at approximately 1ng/mL as capture antibody.

CTNNA1 polyclonal antibody
PAB7024
Immunohistochemistry staining of paraffin embedded human prostate using CTNNA1 polyclonal antibody (Cat# PAB7024) at 3.8μg/mL.

References
Tee, Y.H., et. al (2015). Nature Cell Biology. DOI: 10.1038/ncb3137
Fletcher, G.C., et.al.(2015). EMBO Journal. DOI 10.15252/embj.201489642
Couderc, C., et.al. (2015). Molecular and Cellular Endocrinology. DOI:10.1016/j.mce.2014.09.006

New Products

  42 High quality Metabolism Assay Kits for the detection and quantification of target proteins
15 Cancer research related new products
 

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2014年10月16日 星期四

糖尿病研究專用利器:亞諾法最新ELISA及檢測試劑盒!

Abnova 十月份中文電子報
亞諾法生技(Abnova) 提供了20個最新的ELISA及檢測試劑盒,有利您對於糖尿病及其相關併發症之研究,例如腎功能不全和血管疾病等。這些試劑盒是專門設計用來針對人類或囓齒類動物的脂質過氧化物、糖尿病標記物和糖化蛋白進行定量測量。我們的製造過程擁有卓越的品質控制,可確保您在實驗和臨床研究上的精確性和一致性!

優勢:
  廣泛的目標檢測範圍
靈敏的分析方法與可重複的結果
適用於基礎研究和臨床調查
熱門糖尿病試劑盒:

  ADIPOQ (人類) ELISA Kit
Adipoq (小鼠) ELISA Kit
Adipoq (大鼠) ELISA Kit
C-Peptide ELISA Kit
Igf1 (小鼠) ELISA Kit
Igf1 (大鼠) ELISA Kit
IGFBP3 (人類) ELISA Kit
Insulin (人類) ELISA Kit
LEP (人類) ELISA Kit
RETN (人類) ELISA Kit
 
更多糖尿病相關研究工具:

  單株抗體
多株抗體
MaxPab抗體
配對抗體
重組蛋白
螢光原位雜交(FISH)探針
ELISA試劑盒
以細胞為基底的ELISA試劑盒
哺乳動物過度表達之細胞溶解物
SiRNA/ RNA-DNA嵌合體
 
最新相關文獻:

 
Identification and validation co-differentially expressed genes with NAFLD and insulin resistance. Wang XC, Zhan XR, Li XY, Yu JJ and Liu XM. Endocrine. 2014 Apr 4. [Epub ahead of print]
所使用的亞諾法產品: Insulin (Human) ELISA Kit

Co-Administration of Metformin and N-Acetyl Cysteine Fails to Improve Clinical Manifestations in PCOS Individual Undergoing ICSI. Cheraghi E, Soleimani Mehranjani M, Shariatzadeh MA, Nasr Esfahani MH, Ebrahimi ZInt J Fertil Steril. 2014 Jul;8(2):119-28.
所使用的亞諾法產品: LEP (Human) ELISA Kit

Effects of chenodeoxycholic Acid on the secretion of gut peptides and fibroblast growth factors in healthy humans. Meyer-Gerspach AC, Steinert RE, Keller S, Malarski A, Schulte FH and Beglinger CJ. Clin Endocrinol Metab. 2013 Aug;98(8):3351-8.
所使用的亞諾法產品: C-Peptide ELISA Kit
 
   
想進一步瞭解其他含最新文獻之糖尿病相關試劑盒產品嗎? 請見完整列表>>  
 
其他最新產品:

  單株抗體
MaxPab抗體
配對抗體
重組蛋白
哺乳動物過度表達之細胞溶解物
螢光原位雜交(FISH)探針
 

contact us
Info telephone