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2015年12月2日 星期三

TGFβ Signaling Pathway


New Discoveries on TGFβ Signaling Pathway
  • ITGBL1, as an upstream effector of TGFβ signaling pathway, is a key contributor to osteomimetic breast cancer. (Cancer Research,2015)
  • Through the activation of TGFβ signaling pathway, HOXB7 promotes malignant tumor progression in cell-autonomous and non-cell-autonomous manners. (Cancer Research,2015)
  • Colon carcinogenesis is strongly associated with genetic mutations in TGFβ signaling pathway of inflamed and regenerating intestinal mucosa. (Cancer Research,2015)

TGFβ / SMAD Signaling Pathway
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References
Li, X.-Q., et.al. (2015). Cancer Research. DOI:10.1158/0008-5472.CAN-15-0240
Liu, S., et.al. (2015). Cancer Research. 10.1158/0008-5472.CAN-14-3100
Oshima H., et. al. (2015). Cancer Research. DOI:10.1158/0008-5472.CAN-14-2036

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